High Sensitivity C-Reactive Protein (hs-CRP) ELISA

Enzyme immunoassay for the quantitative determination of C-Reactive Protein in human serum.

INTENDED USE:For the quantitative determination of C-Reactive Protein by an enzyme immunoassay in human serum.

GENERAL INFORMATION:C-reactive protein (CRP) is a pentameric acute phase reactant that is synthesized by the liver. Its production is controlled primarily by interleukin-6. The serum CRP concentration may increase by up to 1000-fold with infection, trauma, surgery, and other acute infl ammatory events. Chronic infl ammatory disorders such as auto-immune diseases and malignancy can produce persistent high levels of serum CRP. Traditionally, CRP has been used clinically for the diagnosis and monitoring of auto-immune and infectous disorders. Recent studies have shown that chronic infl ammation is an important component in the development and progression of atherosclerosis. As a result, increased serum CRP concentration are positively associated with the risk of future coronary events.

KIT CHARACTERISTICS:
- Method: ELISA
- Tests: 96
- Incubation Time / Conditions: 30, 15, 10-15 min (RT/shaker)
- Standard Range: 100 - 10,000 ng/ml
- Sensitivity analytical: 10 ng/ml
- Final Sample Volume: 20 µl
- Sample Type: serum
- Sample Pretreatment: dilution 1:20
- Isotope / Substrate: TMB 450 nm
- Internal Controls: 2
- Regulatory Status: CE