GIP Active form human ELISA

Enzyme immunoassay for the quantitative determination of active form human GIP in EDTA-plasma.

INTENDED USE: This assay kit is capable for the quantitative determination active form human GIP in EDTA-plasma. For research use only, not for use in diagnostic procedures.

GENERAL INFORMATION:ncretins are a group of gastrointestinal hormones that cause an increase in the amount of insulin released from the beta cells of the islets of Langerhans after eating and they also inhibit glucagon release from the alpha cells of the Islets of Langerhans. GIP, typical incretin like GLP-1, was isolated and sequenced from intestinal mucosa as “gastric inhibitory peptide” in 1970, and then it was renamed as “glucosedependent insulinotropic peptide”. It has been reported that GIP receptor is expressed in cells such as beta cell of pancreas, adipocyte or osteoblastic cell, and it plays essential roles in reserving of ingested nutrients within the body in each cell, and the control of GIP signal can lead to improvement of metabolic syndrome. It is rapidly inactivated to GIP (3-42) from active form of GIP (1-42) by DPP-IV in blood. This ELISA kit can measure only active form of Human GIP (1-42).

KIT CHARACTERISTICS:
- Method: ELISA
- Tests: 96
- Incubation Time / Conditions: 1 h (37°C), 1 h (4°C), 30 min (RT)
-Standard Range: 1.6 - 100 pg/ml
- Sensitivity analytical: 1.2 pg/ml
- Final Sample Volume: 100 µl
- Sample Type: plasma (EDTA)
- Isotope / Substrate: TMB 450 nm
- Regulatory Status: RUO