Anti-Müllerian Hormone (AMH) ELISA

Enzyme immunoassay for the quantitative measurement of Anti-Müllerian Hormone (AMH) in serum or plasma.

INTENDED USE:The DEMEDITEC AMH ELISA is a manual enzyme immunoassay for the quantitative measurement of Anti-Müllerian Hormone (AMH) in human serum or plasma (EDTA or Li-heparin plasma). For in vitro diagnostic use. For laboratory professional use.

GENERAL INFORMATION:Anti-Müllerian Hormone (AMH), a dimeric 140 KDa glycoprotein, is a member of the transforming growth factor-β (TGF-β) family of cytokines which plays an essential role in the normal differentiation of reproductive structures. AMH is secreted by Sertoli cells of the testes during embryogenesis of the fetal male, preventing the development of the Müllerian ducts to the uterus and other Müllerian structures. In females, AMH is secreted by the granulosa cells of ovarian follicles. AMH has been identified as a reliable marker of ovarian reserve that can help predict early ovarian follicle loss and menopause onset. AMH levels also reflect the effects of damaging gynecologic surgeries or gonadotoxic treatments such as chemotherapy on ovarian reserve. Furthermore, AMH contributes in the diagnosis of polycystic ovary syndrome (PCOS).

KIT CHARACTERISTICS:
- Method: ELISA
- Tests: 96
- Incubation Time / Conditions: 1 h, 15 min (RT)
- Standard Range: 0.4 - 20 ng/ml
- Sensitivity analytical: 0.044 ng/ml
- Final Sample Volume: 25 µl
- Sample Type: serum, plasma (EDTA, Li-heparin)
- Isotope / Substrate: TMB 450 nm
- Internal Controls: 2
- Regulatory Status: CE