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Bio-Shield 2019-Ncov Igm Immunoglobulin
Item code
C1296
Technology
ELISA
Manufacturer
Prognosis Biotech
Variants
96 Tests
49
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Semi-quantitative ELISA test of 48 or 96 wells quantifying IgM antibodies against SARS-CoV-2 in human serum or plasma (Heparin, EDTA or Citrate) specimens.
GENERAL INFORMATION:
Coronaviruses are enveloped, positive-sense and single-stranded RNA viruses with a nucleocapsid of helical symmetry and are composed of several proteins including the Spike (S), Envelope (E), Membrane (M) and Nucleocapsid (N) proteins. The S protein is very immunogenic with the Receptor Binding Domain (RBD) being the target of many neutralizing antibodies. The 2019 SARS-CoV-2 emerged in the Chinese province of Hubei (Wuhan) in December 2019 and has been declared a pandemic on 11 March 2020. This outbreak has spread rapidly, with millions of reported cases and thousands of deaths worldwide. Currently, there is no medication or vaccine available against infection with this new virus. Antibodies are produced by the immune system after an average of 7 days after infection. The Immunoglobulins M and A and G are produced in response of the infection and the Seroconversion for IgG and IgM occurs simultaneously or sequentially. Both IgG and IgM titers reach a plateau within 6 days after seroconversion. Within 19 days after symptom onset, all patients tested are positive for IgG against SARS-CoV-2. Serological testing may be helpful for the diagnosis of suspected patients with negative RT–PCR results (determining the number of cases of COVID-19) and for the identification of asymptomatic infections.
LATERAL FLOW KIT CHARACTERISTICS:
-Semi-quantitative ELISA test with single-break strip plate with 48 wells (6 strips) or 96 wells (12 strips)
-Clinical Diagnostic Sensitivity 82.66%, 62/75 (CI: 0.7257 to 0.8958), Clinical Diagnostic Specificity 100%, 91/91 (CI: 0.9595 to 1)
-Ιnternal validation results: 92.31%, 72/78 (CI: 0.8422 to 0.9643) sensitivity & 99.85%, 666/667 (CI: 0.9916 to 0.9997) specificity
-Test time: 90 min
-Compatible with automated ELISA systems
-Shelf Life: 12 months | Storage 2-8 °C
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PCR - Laminar Flow Chambers (3)
Spectrophotometers (2)
Ultrasounds - Sonicators (2)
Water Purifier (2)
Food (242)
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Food adulteration (28)
Food allergens (67)
Food safety (45)
Genetically modified organisms (GMO) (6)
Mycotoxins (40)
Plant pathogens (27)
Water quality (19)
Other food tests (7)
Human (126)
Bacteria (51)
Covid-19 tests (16)
Fungi (8)
Parasites (7)
Virus (42)
General laboratory solutions (176)
Antibiotics, enzymes and buffers (23)
Cloning and cell research (27)
Culture media (27)
DNA/RNA amplification and analysis (42)
DNA/RNA extraction and purification (40)
Plasticware (17)
Veterinary (378)
Bacteria (171)
Fungi (9)
Hormones (5)
Parasites (29)
Virus (158)
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